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This shape allows it to fit perfectly into receptors in the body, like a key fitting into a lock

But Novo Nordisk says this condition is a very rare eye disease and is not an adverse drug reaction for semaglutide

Proper management requires immediately discontinuing the phenylephrine and utilizing -adrenergic antagonists (such as phentolamine or tolazoline) or direct vasodilators (such as hydralazine or nicardipine) to safely lower blood pressure (Ebert 2026, Medical Advisory Board 2026a)

And these medications are also originally for diabetes